Abstract P25. Hyberbaric Normothermic Perfusion Mitigates Reperfusion Injury in Porcine Vascular Composite Allotransplantation (VCA)
نویسندگان
چکیده
PURPOSE: Patients undergoing autologous breast reconstruction are at high risk of perioperative venous thromboembolic events (VTE). The efficacy of chemoprophylaxis in decreasing VTE is well established but the timing of chemoprophylaxis remains controversial. Many surgeons are reluctant to initiate preoperative chemoprophylaxis due to concerns of bleeding. We compare the incidence of bleeding following preoperative versus postoperative initiation of chemoprophylaxis in microvascular breast reconstruction.
منابع مشابه
Hyperbaric Sub-Normothermic Ex-Vivo Perfusion Delays the Onset of Acute Rejection in a Porcine VCA Model.
INTRODUCTION: Vascularized composite allotransplantation (VCA) offers superior functional recovery following devastating maxillofacial and upper limb injuries compared to traditional reconstructive techniques. Here, we evaluate the efficacy of a novel sub-normothermic (SN) ex-vivo perfusion strategy using hyper-oxygenated University of Wisconsin (UW) solution to mitigate reperfusion injury (RI)...
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Vascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods. VCAs consist of blocks of functional units comprising different tissue types such as skin, bone, muscle, nerves, blood vessels, tendons, ligaments and others, and are thus substantially different from the compositio...
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Reconstructive transplantation, also referred to as vascularized composite allotransplantation (VCA), has rapidly emerged as a viable approach to repairing complex tissue defects. Over the past 20 years, major advances have been made in the field of VCA allowing for successful transplantation of over 150 hand/forearm/arm, larynx, trachea, abdominal wall, vascularized knee, and facial transplant...
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The emerging field of vascular composite allotransplantation (VCA) has become a clinical reality. Building upon cutting edge understandings of transplant surgery and immunology, complex grafts such as hands and faces can now be transplanted with success. Many of the challenges that have historically been limiting factors in transplantation, such as rejection and the morbidity of immunosuppressi...
متن کاملAbstract: 8.30 Subnormothermic Machine Perfusion (Snmp) With A Novel Hemoglobin-Based Oxygen Carrier (Hboc) Solution For Ex Vivo Preservation In Vascularized Composite Allotransplantation (Vca)
T husday, M ay 6, 2016 retrograde IMV except one patient who used the IMV and an IMV perforator. Over the time period, there was an increasing use of perforator DIEP and SIEA flaps as well as the use of the IMV as recipients. Complications included delayed wound healing (n=5), abdominal bulge (n=2), cellulitis (n=3), seroma (n=2), and fat necrosis (n=3). There was one partial flap loss where th...
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2017